This hub offers a wide array of tools, publications, and other media to assist researchers working in contraception and prevention of HIV and other STIs in keeping end-users in mind from the beginning and throughout the product development life cycle.

Why a socio-behavioral research hub for the MPT field?

  • There are many complexities in developing MPTs that will be safe, effective, affordable, and used by women.
  • One key aspect of this process is to study the desirability and acceptability of an MPT candidate during its development so that, when it reaches the market, women will actually use it.
  • It is essential for multidisciplinary experts—including those with expertise in HIV, other STIs, contraception, socio-behavioral and market research, drug development, and clinical research—to connect and collaborate to facilitate integration of end-user research throughout different phases of product development.

Browse our featured categories to find the right resources to support your work!

Journal Articles

  • Exploring the potential of vaginal drug delivery: innovations, efficacy, and therapeutic prospects (2025)
  • Vaginally-delivered fast-dissolving antibody tablets (FDAT) for on-demand non-hormonal contraception and multi-purpose protection (2025)
  • Frontiers in Reproductive Health: Regulatory Pathways and Challenges in MPT Development (2025)
  • Acceptability of an annual tenofovir alafenamide implant for HIV prevention in South African women: findings from the CAPRISA 018 Phase I clinical trial (2025)
  • We choose: Adolescent girls and young women’s choice for an HIV prevention product in a cross-over randomized clinical trial conducted in South Africa, Uganda, and Zimbabwe (2024)
  • Service Delivery Preferences for Long-acting Pre-exposure Prophylaxis among Pregnant and Breastfeeding Women in South Africa and Botswana (2024)
  • Perception of couples’ on multipurpose prevention technology attribute choice: the case of MTN 045 (2024)
  • “Something Like That”: Awareness and Acceptability of HIV PrEP and PEP Among Kenyan Adolescents (2024)
  • Prevention method preferences and factors influencing hypothetical choice among women in South Africa: a survey exploring opportunities for a multipurpose prevention technology implant (2024)
  • Ending HIV Transmission in Australia: Expanding PrEP to Cisgender Women: A Scoping Review (2024)
  • Multipurpose prevention technologies: Determination of an interest in its use for STI and contraception by Nigerian women (2024)
  • End-user research into understanding perceptions of and reactions to a microarray patch (MAP) for contraception among women in Ghana, Kenya and Uganda (2024)
  • Estimating the costs and perceived benefits of oral pre-exposure prophylaxis (PrEP) delivery in ten counties of Kenya: a costing and a contingent valuation study (2024)
  • Vagina, a promising route for drug delivery (2024)
  • Factors influencing the uptake of a mono-PrEP implant for the prevention of HIV: Males’ perspectives from three South African provinces (2024)
  • Factors influencing the uptake of a mono-PrEP implant for the prevention of HIV: Males’ perspectives from three South African provinces (2024)
  • Another Best Practice: Leveraging User and Stakeholder Perspectives to Improve and Refine Existing Medical Products (2023)
  • Assessing Per-Sex-Act HIV-1 Risk Reduction Among Women Using the Dapivirine Vaginal Ring (2023)
  • Implementing Differentiated and Integrated PrEP Services for Adolescent Key Populations: What Works and What Is the Way Forward? (2023)
  • Corrigendum: How might we motivate uptake of the Dual Prevention Pill? Findings from human-centered design research with potential end users, male partners, and healthcare providers (2023)
  • HIV epidemiology, prevention, treatment, and implementation strategies for public health (2023)
  • Turning the promise of multipurpose prevention technologies into a market reality: a commentary (2023)
  • US Women’s Preferences, Acceptability and User Experiences with Three Different Intravaginal Rings Varying in External Diameter: A Qualitative Study (2023)
  • Preferences for Long-Acting PrEP Products Among Women and Girls: A Quantitative Survey and Discrete Choice Experiment in Eswatini, Kenya, and South Africa (2023)
  • Preferences, educational messaging, and demand creation channels for multipurpose-prevention technologies (MPTs) among women in South Africa (2023)
  • Measuring Effects of Counseling to Increase Pre-Exposure Prophylaxis Adherence and Partner Support in South Africa Using the Healthy Relationship Assessment Tool (2023)
  • Attitudes Toward Menstrual Suppression Among Cyclic and Continuous Contraceptive Vaginal Ring Users in Kenya (2023)
  • Systematic review of the values and preferences regarding the use of injectable pre-exposure prophylaxis to prevent HIV acquisition (2023)
  • Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a phase 1 clinical trial: learning from users to improve acceptability (2023)
  • Baseline preferences for oral pre-exposure prophylaxis (PrEP) or dapivirine intravaginal ring for HIV prevention among adolescent girls and young women in South Africa, Uganda and Zimbabwe (MTN-034/IPM-045 study) (2023)
  • Synthesis of end-user research to inform future multipurpose prevention technologies in sub-Saharan Africa: a scoping review (2023)
  • Optimizing the pipeline of multipurpose prevention technologies: opportunities across women’s reproductive lifespans (2023)
  • Cost-effectiveness of the dual prevention pill for contraception and HIV pre-exposure prophylaxis (2023)
  • Prospective acceptability of a multipurpose technology (MPT) implant in preclinical development to prevent HIV and unplanned pregnancy: Qualitative insights from women end users and health care providers in South Africa and Zimbabwe (2023)
  • Microarray patch for HIV prevention and as a multipurpose prevention technology to prevent HIV and unplanned pregnancy: an assessment of potential acceptability, usability, and programmatic fit in Kenya (2023)
  • Preferred product attributes of a multipurpose vaginal ring: Findings from a phase 1 trial (2023)
  • Women Want Choices: Opinions from the Share.Learn.Shape Global Internet Survey About Multipurpose Prevention Technology (MPT) Products in Development (2023)
  • Incorporating end-users’ voices into the development of an implant for HIV prevention: a discrete choice experiment in South Africa and Zimbabwe (2023)
  • Interrogating the promise of long-acting HIV pre-exposure prophylaxis (2022)
  • Acceptability of an intravaginal ring for simultaneously preventing HIV infection and pregnancy: Qualitative findings of the Kisumu Combined Ring Study, 2019 (2022)
  • Making the Case for Joint Decision-Making in Future Multipurpose Prevention Technology (MPT) Choice: Qualitative Findings on MPT Attribute Preferences from the CUPID Study (MTN-045) (2022)
  • HIV prevention for the next decade: Appropriate, person-centred, prioritised, effective, combination prevention (2022)
  • Acceptability of a Long-Acting, Multipurpose Vaginal Ring: Findings from a Phase I Trial in the U.S. and Dominican Republic (2022)
  • Correlates of Dapivirine Vaginal Ring Acceptance among Women Participating in an Open Label Extension Trial (2022)
  • Mechanisms of action of currently available woman-controlled, vaginally administered, non-hormonal contraceptive products (2022)
  • Partner violence as conversation opener for preexposure prophylaxis use among younger women (2022)
  • Couples’ decision making regarding the use of multipurpose prevention technology (MPT) for pregnancy and HIV prevention (2022)
  • Couples’ Preferences for “2 in 1” Multipurpose Prevention Technologies to Prevent Both HIV and Pregnancy: Results of a Discrete Choice Experiment in Uganda and Zimbabwe (2022)
  • Efficacy and Action of the Dapivirine Vaginal Ring as Understood by Women Participating in an Open Label Extension Study (2022)
  • Preferences for Multipurpose Technology and Non-oral Methods of Antiretroviral Therapy Among Women Living With HIV in Western Kenya: A Survey Study (2022)
  • Female and male partner perspectives on placebo Multipurpose Prevention Technologies (MPTs) used by women in the TRIO study in South Africa and Kenya (2022)
  • Design, adaptation, and diffusion of an innovative tool to promote shared contraceptive decision-making: Balanced Counseling Strategy Plus (2022)
  • HIV Pre-exposure Prophylaxis Implant Stated Preferences and Priorities: Results of a Discrete Choice Experiment Among Women and Adolescent Girls in Gauteng Province, South Africa (2022)
  • HIV prevention: better choice for better coverage (2022)
  • Overlapping needs for sexual and reproductive health and HIV prevention in women with substance use disorders (2022)
  • Advances in long-acting injectables, implants, and vaginal rings for contraception and HIV prevention (2021)
  • Giving Voice to the End-User: Input on Multipurpose Prevention Technologies From the Perspectives of Young Women in Kenya and South Africa (2021)
  • Estimating the market size for a dual prevention pill: adding contraception to pre-exposure prophylaxis (PrEP) to increase uptake (2021)
  • Microarray patches: Breaking down the barriers to contraceptive care and HIV prevention for women across the globe (2021)
  • HIV prevention is not all about HIV – using a discrete choice experiment among women to model how the uptake and effectiveness of HIV prevention products may also rely on pregnancy and STI protection (2020)
  • Insights for Implementation Science From 2 Multiphased Studies With End-Users of Potential Multipurpose Prevention Technology and HIV Prevention Products (2019)
  • “We are not the same”: African women’s view of multipurpose prevention products in the TRIO clinical study (2019)
  • Young women’s stated preferences for biomedical HIV prevention results of a discrete choice experiment in Kenya and South Africa (2019)
  • A strategic action framework for multipurpose prevention technologies combining contraceptive hormones and antiretroviral drugs to prevent pregnancy and HIV (2018)
  • Dual HIV and pregnancy prevention cost effective? (2018)
  • Effectiveness of female condom in preventing HIV and sexually transmitted infections: a systematic review protocol (2018)
  • The Tablets, Ring, Injections as Options (TRIO) study: what young African women chose and used for future HIV and pregnancy prevention (2018)
  • Young Women’s Ratings of Three Placebo Multipurpose Prevention Technologies for HIV and Pregnancy Prevention in a Randomized, Cross-Over Study in Kenya and South Africa (2018)
  • The cost-effectiveness of multi-purpose HIV and pregnancy prevention technologies in South Africa (2018)
  • End-users’ product preference across three multipurpose prevention technology delivery forms: Baseline results from young women in Kenya and South Africa (2018)
  • Vaginal Film for Prevention of HIV: Using Visual and Tactile Evaluations among Potential Users to Inform Product Design (2017)
  • The promise of multipurpose pregnancy, STI, and HIV prevention (2017)
  • Indigenous HIV Prevention Beliefs and Practices Among Low-Earning Chinese Sex Workers as Context for Introducing Female Condoms and Other Novel Prevention Options (2016)
  • Qualitative Analysis of Sexually Experienced Female Adolescents: Attitudes about Vaginal Health (2016)
  • Knowledge, attitudes, practices, and behaviors associated with female condoms in developing countries: a scoping review (2016)
  • How to sell a condom? The impact of demand creation tools on male and female condom sales in resource limited settings (2016)
  • Preferences for ARV-based HIV prevention methods among men and women, adolescent girls and female sex workers in Gauteng Province, South Africa: a protocol for a discrete choice experiment (2016)
  • Stated product formulation preferences for HIV pre-exposure prophylaxis among women in the VOICE-D (MTN-003D) study (2016)
  • Nonuse of contraception among women at risk of unintended pregnancy in the United States (2015)
  • The FACTS about women and pre-exposure prophylaxis (2015)
  • Acceptability and preferences for vaginal dosage forms intended for prevention of HIV or HIV and pregnancy (2015)
  • Engaging male partners in women’s microbicide use: evidence from clinical trials and implications for future research and microbicide introduction (2014)
  • An interdisciplinary framework for measuring and supporting adherence in HIV prevention trials of ARV-based vaginal rings (2014)
  • Contraception and prevention of HIV transmission: a potential conflict of public health principles (2014)
  • Qualitative research from the VOICE trial reveals women’s challenges in adherence (2014)
  • Efficacy of behavioral interventions to increase condom use and reduce sexually transmitted infections: a meta-analysis, 1991 to 2010 (2011)
  • Baseline correlates of inconsistent and incorrect condom use among sexually active women in the Contraceptive CHOICE Project (2011)

    • Tools

  • TRIO Study Brief: Long-Acting Injections for Women’s HIV Prevention in Sub-Saharan Africa: What End-Users Think (2021)
  • Toward a Roadmap for Biomedical HIV Prevention Investment Standards: Strategic Insights from Key Industry Stakeholders (2019)
  • Market Access Framework for Multipurpose Prevention Technology (MPT) Development and Introduction (2019)
  • MPT Target Population Identification Mapping Tool (2019)
  • Traditional Socio-Behavioral Research and Human-Centered Design: Similarities, Unique Contributions and Synergies (2017)
  • Building MPT acceptability during product development through consumer and health systems research (2017)
  • MPTs: Building momentum through awareness-raising and advocacy (2017)
  • Multipurpose Prevention Technologies (MPTs): Innovation to Protect Women’s Reproductive Health in Kenya (2014)
  • Global Reproductive Health Diaries (2013)

    • Reports

  • A Thought Paper on Fostering Greater Utilization of Social and Behavioural Research in The Development Setting and Creating Impact (2022)
  • Multipurpose Prevention Technologies: Technology Landscape and Potential for Low- and Middle-Income Countries (2021)
  • Dual Prevention Pill: A Summary of Insights and Recommendations on the uptake of the combined PrEP and Oral Contraceptive pill by women of reproductive age in South Africa and Zimbabwe (2021)
  • Recommendations and Solutions from Human-Centered Design Research on the Dual Prevention Pill (2021)
  • Microbicide Trials Network (MTN) Socio-behavioral Research Compendium (2021)
  • Exploring intravaginal ring acceptability for disease prevention among at-risk community members in Cape Town (2017)
  • HIV Prevention Products – Dapivirine Ring & Oral Truvada (2017)
  • Understanding consumer preference for HIV prevention products: Quantitative findings from surveys with 18-21 year old young women in South Africa (2017)
  • Understanding consumer preference for HIV prevention products: Qualitative findings from discussions with 18-21 year old young women in South Africa (2017)
  • The importance of sexual and reproductive health and rights to prevent HIV in adolescent girls and young women in eastern and southern Africa (2017)
  • MPTs – Strategy, Research & Product Development (2016)
  • Assessing the Potential of MPTs in South Africa, Uganda and Nigeria (2014)
  • Meeting Report: International Symposium on Accelerating Research on Multipurpose Prevention Technologies for Reproductive Health (2013)
  • Developing a Strategy for Female Condom Parallel Programming (2011)
  • Female Condoms and U.S. Foreign Assistance: An Unfinished Imperative for Women’s Health (2011)

    • Webinars

  • Evaluating Vaginal MPT Product Performance Using Experimental and Computational Modeling Approaches (2025)
  • Unlocking the Potential of MPTs: Funding Trends for MPTs, HIV/STIs, Contraception (2025)
  • If you build it, will they come? Incorporating end-user needs into MPT research (2024)
  • Demand for Novel Male Contraceptives & Requisite Need for Development of Male MPTs in Select LMICs (2023)
  • Considerations when Transitioning an MPT Product Candidate from Preclinical to Clinical Development (2022)
  • Integrating End-User Research in MPT Product Development & Commercialization Strategies (2022)
  • Integrating Socio-behavioral & Market Research into MPT R&D: Applying Lessons Learned (2021)
  • MPT End-User Research: Updates from the Field (2017)

    • Presentations

  • Exploring the R&D Landscape and Potential of Multipurpose Prevention Technologies (2022)
  • Market Assessment Needs for MPTs – The Human Factor: Applications for Product Development & Early Stage Clinical Trials (2016)
  • Multipurpose Prevention Technologies (2014)
  • Round Table Discussion: Multipurpose Prevention Technologies (2014)
  • Introducing Novel Technologies at the Country Level; Promoting Approval, Access and Acceptance (2013)
  • MPTs: Assessing Acceptability and Adherence (2013)
  • The Reality on the Ground: What Users and Providers Want and Need in MPTs (2013)
  • Indian women’s perceptions of vaginal rings-feedback for development of multipurpose prevention technologies (2013)
  • What do these technologies mean for women living with HIV? (2013)
  • What Have We Learned From Other Reproductive Health Technologies? (2012)
  • Users’ and Providers’ Perspectives on MPTs: What do we know, and what do we need to know? (2012)
  • Involving End Users and Health System in the Development of/Access to MPTs: The Indian context (2012)
  • Availability, Access and Utilization of MPTs: Issues and Challenges (2012)

    • Media

  • Multipurpose Prevention Technologies: Call for Innovative Strategies to Address Critical Priorities and Gaps (2024)
  • Sexual Satisfaction Results With the Vaginal pH Modulator From the Phase 3 AMPOWER Study (2022)
  • Watch: Now a rap song to promote use of condoms (2019)
  • ‘Female condom’ gets a genderless rebrand from FDA (2019)
  • African women prefer multipurpose HIV prevention products (2019)
  • Maximise benefits of female condom, physician counsels women (2019)
  • Survey reveals high number of sexually active women who use no birth control method, supporting the continued need for non-hormonal birth control innovations such as Evofem Biosciences’ Amphora (2018)
  • Celebrating #NextGenContraception on World Contraception Day (2018)
  • ‘Now, few takers for ‘government condoms’ as users look for other options’ (2018)
  • Women around the world lack access to comprehensive contraception-this is the solution (2018)
  • Contraceptive technology innovation: It’s everyone’s business (2018)
  • Getting behind human-centered design for contraceptive innovation (2018)
  • 3D printed intravaginal rings to help protect women from HIV infection and unintended pregnancy (2018)
  • Human-centered design and socio-behavioral research: scientific rigor with a dash of savvy and spice (2018)
  • World Contraception Day: Body calls on stakeholders to make access to modern contraception easy (2018)
  • This week in sex: Does game-changing HIV prevention regimen reduce condom use? (2018)
  • Empowerment – the payoff of new HIV prevention tools for young women (2017)
  • CONRAD launches Quatro in South Africa and Zimbabwe (2016)
  • Competing Priorities: Partner-Specific Relationship Characteristics and Motives for Condom Use Among At-Risk Young Adults (2016)
  • Biomarkers and biometric measures of adherence to use of ARV-based vaginal rings (2016)
  • This Week in Sex: News From the HIV Epidemic (2016)
  • 3 Bodies sensitise women to female condom (2015)
  • H.I.V. Drugs: A Failed Trial [Letter to the editor] (2015)
  • Does New HIV-Prevention Technology Empower or Burden Women? (2014)
  • Can you imagine a world without condoms for safe sex? Scientists can (2014)
  • MPTs as Seen From a Bowl of Salad Combo (2014)
  • As strategies to prevent HIV and unintended pregnancies evolve, concepts of “multi-purpose technologies” raise a familiar question (2014)
  • So When Will the Next Big Thing Be Available for General Use? (2014)
  • The South African HIV scientist who gave girls back control of their bodies (2014)
  • Improving SRH and HIV Integration is key for delivering new multipurpose prevention technologies. (2014)
  • NIH’S Dr. Gina Brown reflects on HIV among women and girls – Highlights from AIDS 2014 (2014)

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