MPT Resource Center

Modern contraception utilization and associated factors among adolescent girls and young women (AGYW) who participated in the Namibia DREAMS program

Moyo, E., Melese, E., Mangwana, H., Takawira, S., Harases, B., Indongo, R., Moyo, P., Makurira Nyoni, N., Dzinamarira, T. December 2025

Artificial neural network guided optimization of tenofovir and Cyanovirin-N multipurpose preventive hydrogel formulation developed using the Box Behnken design model

Oyediran, K.O., Cardoso-Daodu, I.M., Bassey, P.O., Ogundemuren, D.A., Muhammed, R., Ojo, O.E., Amenaghawon, A.N., Azubuike, C.P., Agarwal, R., Haritha, K., Ilomunaya, M.O. December 2025

Advances in drug-releasing vaginal rings

McCoy, C.F., Zhao, X., Shen, X., Bashi, Y.H.D., Murphy, D.J., Boyd, P., Malcolm, R.K. November 2025

A Dual Prevention Pill for HIV & Pregnancy Prevention: A Pilot Study Among Adolescent Girls and Young Women in Zimbabwe

Mgodi, N.M., Burnett-Zieman, J.B., Murombedzi, C., Dandadzi, A., Gatsi, V., Musara, P., Matimbira, S., Mavemwa, G., Jambaya, J., Chidemo, T., Plagianos, M., Haddad, L.B., Bruce, I.V., Mathur, S., Friedland, B.A. November 2025

Alternatives to animal testing are the future — it’s time that journals, funders and scientists embrace them

Herron, T.J., Brüning-Richardson, A., Gough, J.E., Miller, A.F., Pilkington, G.J., Greenman, J., Speirs, V., Wu, J.C. October 2025

Tenofovir and levonorgestrel vaginal MPT film developed via quality by design approach (drug release and safety evaluation in an animal model)

Muhammad, R., Bassey, P. O., Nwaneri, S. C., Cardoso-Daodu, I. M., Oladosu, A. A., Oyediran, K. O., Ilomuanya, M. O. September 2025

“…this could be a noble idea and a game changer.” The potential of a dual prevention pill for HIV and pregnancy prevention among adolescent girls and young women in Zimbabwe.

Dandadzi, A., Mathur, S., Musara, P., Bruce, I., Begg, L., Sedze, N. T., Mutero, P., Mgodi, N. M., Friedland, B. A. August 2025

Predictors Of Dual Protection Use Based On Information-Motivation-Behavior Skill Model Among Female University Students: A Cross-Sectional Study

Feyisa, B. N., Debelew, G. T., Koricha, Z. B. August 2025

Exploring the Safety and Compatibility of a Ready-to-Use Vaginal Film Vehicle for Drug Delivery: A Clinical Assessment

Marianni, B., Silva, C. C. V., Koulouridas, S., Polonini, H. August 2025

Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Non-hormonal Contraception

Ogundemuren, D. A., Bassey, P.-O. O., Oyediran, K. O., Nmesoma, O. G., Tsamos, D., Tsamis, A., Tsouknidas, A. E. June 2025

Exploring the potential of vaginal drug delivery: innovations, efficacy, and therapeutic prospects

Sanchez Armengol, E., Veider, F., Millotti, G., Kali, G., Bernkop-Schnürch, A., Laffleur, F. June 2025

Vaginally-delivered fast-dissolving antibody tablets (FDAT) for on-demand non-hormonal contraception and multi-purpose protection

Kushiro, K., Hammers, S., Zhu, Y., Flowers, H. B., Dawson, L., Panjwani, A., Schaefer, A., Quan, D., Gibb, K., McSweeney, M., Cone, R., Moench, T., Vincent, K. L., Lai, S. K. June 2025

Frontiers in Reproductive Health: Regulatory Pathways and Challenges in MPT Development

Donaldson, L., Schaefer, R., Alhakimi, S., Akulu, R., Palanee-Phillips, T., Young Holt B., Miller, V. May 2025

A multipurpose silicone elastomer vaginal ring releasing dapivirine and Cu2+/Zn2+ ions for HIV prevention and non-hormonal contraception

Shen, X., Boyd, P., Dallal Bashi, Y.H., McCoy, C.F., Zhao, X., Malcolm, R.K. April 2025

Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

Vodstrcil, L.A., Plummer, E.L., Fairley, C.K., Hocking, J.S., Law, M.G., Petoumenos, K., Bateson, D., Murray, G.L., Donovan, B., Chow, E.P.F., Chen, M.Y., Kaldor, J., Bradshaw, C.S. March 2025

Acceptability of an annual tenofovir alafenamide implant for HIV prevention in South African women: findings from the CAPRISA 018 Phase I clinical trial

Gengiah, T.N., Heck, C.J., Lewis, L., Mansoor, L.E., Harkoo, I., Myeni, N., Baum, M.M., Moss, J.A., Rooney, J.F., Hankins, C., Pozzetto, B., Abdool Karim, S.S., Abdool Karim, Q. February 2025

Advancing Health Solutions: Practical Considerations for Multipurpose Prevention Technologies in Sub-Saharan Africa’s Fight Against HIV, Sexually Transmitted Infections, and Unintended Pregnancies

Mgodi, N.M., Murombedzi, C., Murewanhema, G., Moyo, E., Dzinamarira, T. January 2025

Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development

Friedland, B.A., Gundacker, H., Achilles, S.L., Chen, B.A., Hoesley, C., Richardson, B.A., Kelly, C.W., Piper, J., Johnson, S., Devlin, B., Steytler, J., Kleinbeck, K., Dangi, B., Friend, C., Song, M., Mensch, B., van der Straten, A., Jacobson, C., Hendrix, C.W., Brown, J., Blithe, D., Hiller, S.L. January 2025

Formulation development of dual-compartment topical inserts combining tenofovir alafenamide and elvitegravir for flexible on-demand HIV prevention

Agrahari, V., Peet, M.M., Chandra, N., Ramalingam, P., Gupta, P.K., Jonnalagadda, S., Singh, O.N., McCormick, T.J., Doncel, G.F., Clark, M.R. January 2025

We choose: Adolescent girls and young women’s choice for an HIV prevention product in a cross-over randomized clinical trial conducted in South Africa, Uganda, and Zimbabwe

Atujuna, M., Williams, K., Roberts, S.T., Young, A., Browne, E.N., Mangxilana, N.T., et al. August 2024

Harnessing private sector strategies for family planning to deliver the Dual Prevention Pill, the first multipurpose prevention technology with pre‐exposure prophylaxis, in an expanding HIV prevention landscape

Verde Hashim, C., Llewellyn, E., Wood, R., Brett, T., Chinyanga, T., Webb, K., & Segal, K. August 2024

Paving the Way for Multi-Purpose Technologies: Programming for Choice and Strengthening Integrated HIV and Sexual and Reproductive Health Services

Rodrigues, J.; Vahle, K.; Mason, J.; Tluway, E.; Buthelezi, B. August 2024

Tailoring drug release from long-acting contraceptive levonorgestrel intrauterine systems

Fanse, S.; Bao, Q.; Zou, Y.; Wang, Y.; Burgess, D.J. August 2024

Summary of the Centers for Disease Control and Prevention/National Institute of Allergy and Infectious Diseases Joint Workshop on Genital Herpes: 3–4 November 2022

Connolly, K.L.; Bachmann, L.; Hiltke, T.; Kersh, E.N.; Newman, L.M.; Wilson, L.; Mena, L.; Deal, C. August 2024

Next-Generation Contraceptive Intravaginal Ring: Comparison of Etonogestrel and Ethinyl Estradiol In Vitro and In Vivo Release from 3D-Printed Intravaginal Ring and NuvaRing

Young, I.C.; Thorson, A.L.; Cottrell, M.L.; Sykes, C.; Schauer, A.P.; Sellers, R.S.; Janusziewicz, R.; Vincent, K.L.; Benhabbour, S.R. August 2024

Service Delivery Preferences for Long-acting Pre-exposure Prophylaxis among Pregnant and Breastfeeding Women in South Africa and Botswana

De Vos, L., Mussa, A., Rousseau, E., et al. July 2024

Injectable long-acting formulations (ILAFs) and manufacturing techniques

Thapa Magar, K.; Boucetta, H.; Zhao, Z.; Xu, Y.; Liu, Z.; & He, W. July 2024

Perception of couples’ on multipurpose prevention technology attribute choice: the case of MTN 045

Dandadzi, A.; Young, A.M.; Musara, P. et al. July 2024

Update on the research on the antigens of anti-sperm antibodies over the last decade

Chen, Y.; Hasegawa, A.; Wakimoto, Y.; Shibahara, H. July 2024

Neutralizing the threat: harnessing broadly neutralizing antibodies against HIV-1 for treatment and prevention

Becerra, J. C.; Hitchcock, L.; Vu, K.; Gach, J. S. July 2024

“Something Like That”: Awareness and Acceptability of HIV PrEP and PEP Among Kenyan Adolescents

Miller, L.; Otieno, B.; Amboka, S. et al. June 2024

Prevention method preferences and factors influencing hypothetical choice among women in South Africa: a survey exploring opportunities for a multipurpose prevention technology implant

Martin, C.E.; Kutywayo, A.; Mataboge, P.; Chidumwa, G.; Mthimkhulu, N.; Bothma, R.; Mullick, S. June 2024

Contraceptive technology is failing to meet the needs of people in the United States because of underinvestment in new methods

Cairns-Smith, S.; Jaffe, H.K.; Speidel, J.J. June 2024

Phase 1 randomized trials to assess safety, pharmacokinetics, and vaginal bleeding associated with use of extended duration dapivirine and levonorgestrel vaginal rings

Achilles, S.L.; Kelly, C.W.; Hoesley, C.J.; Blithe, D.L.; Brown, J.; Richardson, B.A., et al. June 2024

Ending HIV Transmission in Australia: Expanding PrEP to Cisgender Women: A Scoping Review

MacPhail, C.; Manlik, K.; Dews, H.; Mao, L.; Rutherford, A. May 2024

Hypotonic, gel-forming delivery system for vaginal drug administration

Shapiro, R.L.; Bockley, K.M.; Hsueh, H.T.; Appell, M.B.; Carter, D.M.; Ortiz, J.; Brayton, C.; Ensign, L.M. May 2024

Editorial: Multipurpose prevention technologies: call for innovative strategies to address critical priorities and gaps

Soh, C.; van der Straten, A.; Hemmerling, A.; Turpin, J.A.; Young Holt, B. May 2024

Vaginal drug delivery system: A promising route of drug administration for local and systemic diseases

Tamil Mani Subi, M.; Selvasudha, N.; Vasanthi, H.R. May 2024

Lessons learnt from daily oral PrEP delivery to inform national planning for PrEP ring introduction for women in low-income and middle-income countries: a qualitative inquiry of international stakeholders

Heck, C.J.; Dam, A.; Yohannes, K.; Deacon, J.; Kripke, K.; Meyers, K.; Poku, O.; Obermeyer, C.; Wiant, S.; Quigee, D.; Larson, M.; Malati, C.; Sobieszczyk, M.E.; Torres-Rueda, S.; Castor, D. May 2024

Multipurpose prevention technologies: Determination of an interest in its use for STI and contraception by Nigerian women

Joda, A. E.; Akapo, A.; Ilomuanya, C. S.; Ogundemuren, D. A.; Ofonabasi-Bassey, P.; Ilomuanya, M. April 2024

A conjoint experiment of three placebo rectal products used with receptive anal sex: results from MTN-035

Bauermeister, J., Lin, W., Tingler, R., Liu, A., Chariyalertsak, S., Hoesley, C., Gonzales, P., Ho, K., Kayange, N., Phillips, T.P., Johnson, S., Brown, E., Zemanek, J., Jacobson, C.E., Doncel, G.F., Piper, J. March 2024

Determination of multipurpose prevention technology choice for contraception and HIV/STI prevention: A survey of sexually active women in Nigeria

Ilomuanya, M.O., Joda, A.E., Adeyemi O.C., et al. March 2024

End-user research into understanding perceptions of and reactions to a microarray patch (MAP) for contraception among women in Ghana, Kenya and Uganda

El-Sahn, M., Elliott, R., El-Sahn, M., Lucas, J. and Wood Santos, T. March 2024

‘ARVs are a constant reminder of lost freedom, whereas for others, they are liberating’: understanding the treatment narrative among people living with HIV (PLHIV) in Malawi and Zimbabwe–a qualitative study

Gumede-Moyo, S., Sharma, S., Gwanzura, C., et al February 2024

Developability assessment of the therapeutic antibodies studies: are they druggable?

Fu, C., Chen, Q.C. February 2024

Estimating the costs and perceived benefits of oral pre-exposure prophylaxis (PrEP) delivery in ten counties of Kenya: a costing and a contingent valuation study

Forsythe, S., Kioko, U., Mahiane, G., Glaubius, R., Musau, A., Gichangi, A., Reed, J., Were, D. February 2024

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