Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Non-hormonal Contraception
Electrospun fiber drug delivery systems, integrated into multipurpose prevention technologies, offer a promising solution for women facing health risks from HIV/STIs and unmet contraceptive needs by providing on-demand protection in a single dosage form. This study investigates the potential of a multilayer electrospun fiber construct for pH-responsive and sustained release of the HIV microbicide tenofovir (TFV) and the CatSper channel blocker nifedipine (NFP) respectively.
June 2025
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Resource Type:
Journal Article
Journal Article
Resource
Citation:
Authors: Ogundemuren, D. A., Bassey, P.-O. O., Oyediran, K. O., Nmesoma, O. G., Tsamos, D., Tsamis, A., Tsouknidas, A. E.
Health Risks(s):
- HIV
- STI / STD
Product type(s):
- MPTs
Topic(s):
- MPTs
Region(s)
- Global
Additional Keywords:
multipurpose prevention technologies; MPTs; STI; human immunodeficiency virus; vaginal drug delivery